Life Science Buffers

Balanced salt solutions and powders used for molecular, protein, nucleic acid, and cell biology applications including cell culture, electrophoresis, ELISA, and chromatography processes; available in a variety of formulations and grades.

Buffer solutions serve to keep pH (acidity or alkalinity) nearly constant in a variety of chemical and biological applications. For example, a bicarbonate buffer helps maintain the pH of blood, a buffered saline maintains cellular contents at a consistent pH level, and buffers help maintain a narrow pH range for enzymes to function correctly.

Most biological samples used in research are kept at a pH of about 7.4. Common biological buffers used for tissue culture include Dulbeccos phosphate buffered saline (PBS), Tris base, HEPES, MOPS, PIPES, and other formulations developed for specific cell lines or applications. Most buffers used in cell culture are also DNase-, RNase-, and protease-free.

The choice of buffer for a particular biological reaction or site depends on several factors:

Temperature
Desired or target pH
Buffer toxicity (to the system)
Buffer interactions with other system components

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436 – 450 of 3,492 results

436

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Thermo Scientific Chemicals BES, 99+%, for biochemistry

CAS: 10191-18-1 Molecular Formula: C6H15NO5S Molecular Weight (g/mol): 213.25 MDL Number: MFCD00007533 InChI Key: AJTVSSFTXWNIRG-UHFFFAOYSA-N Synonym: N, N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid PubChem CID: 73243 ChEBI: CHEBI:39045 SMILES: OCCN(CCO)CCS(O)(=O)=O

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Specifications

PubChem CID	73243
CAS	10191-18-1
Molecular Weight (g/mol)	213.25
ChEBI	CHEBI:39045
MDL Number	MFCD00007533
SMILES	OCCN(CCO)CCS(O)(=O)=O
Synonym	N, N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid
InChI Key	AJTVSSFTXWNIRG-UHFFFAOYSA-N
Molecular Formula	C6H15NO5S

437

MP Biomedicals™ Tricine

Tricine is for use in electrophoresis buffers.

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438

Tris, MP Biomedicals™

CAS: 77-86-1 Molecular Formula: C4H11NO3 Molecular Weight (g/mol): 121.136 InChI Key: LENZDBCJOHFCAS-UHFFFAOYSA-N Synonym: Trometamol, Tromethamine, Tris-[hydroxymethyl]aminomethane, 2-Amino-2-(hydroxymethyl)-1,3-propanediol PubChem CID: 6503 ChEBI: CHEBI:9754 IUPAC Name: 2-amino-2-(hydroxymethyl)propane-1,3-diol SMILES: C(C(CO)(CO)N)O

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Specifications

PubChem CID	6503
CAS	77-86-1
Molecular Weight (g/mol)	121.136
ChEBI	CHEBI:9754
SMILES	C(C(CO)(CO)N)O
Synonym	Trometamol, Tromethamine, Tris-[hydroxymethyl]aminomethane, 2-Amino-2-(hydroxymethyl)-1,3-propanediol
IUPAC Name	2-amino-2-(hydroxymethyl)propane-1,3-diol
InChI Key	LENZDBCJOHFCAS-UHFFFAOYSA-N
Molecular Formula	C4H11NO3

439

MES, >98%, MP Biomedicals™

CAS: 145224-94-8 Molecular Formula: C6H15NO5S Molecular Weight (g/mol): 213.25 MDL Number: MFCD00149409 InChI Key: MIIIXQJBDGSIKL-UHFFFAOYSA-N Synonym: 2-[N-Morpholino]ethanesulfonic acid PubChem CID: 16218417 IUPAC Name: 2-(morpholin-4-yl)ethane-1-sulfonic acid hydrate SMILES: O.OS(=O)(=O)CCN1CCOCC1

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Specifications

PubChem CID	16218417
CAS	145224-94-8
Molecular Weight (g/mol)	213.25
MDL Number	MFCD00149409
SMILES	O.OS(=O)(=O)CCN1CCOCC1
Synonym	2-[N-Morpholino]ethanesulfonic acid
IUPAC Name	2-(morpholin-4-yl)ethane-1-sulfonic acid hydrate
InChI Key	MIIIXQJBDGSIKL-UHFFFAOYSA-N
Molecular Formula	C6H15NO5S

440

AMP, 0.2M buffer soln., pH 9.5, Thermo Scientific™

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Specifications

Molecular Weight (g/mol)	89.14
Color	Colorless
Physical Form	Liquid
SMILES	CC(C)(N)CO
Concentration	0.2 M
InChI Key	CBTVGIZVANVGBH-UHFFFAOYSA-N
CAS	124-68-5
MDL Number	MFCD00008051
pH	9.5
Synonym	2-Amino-2-methyl-1-propanol
Recommended Storage	Keep cold
IUPAC Name	2-amino-2-methylpropan-1-ol
Molecular Formula	C4H11NO
Odor	Odorless

441

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Tris, PlusOne™, Cytiva

CAS: 77-86-1 Molecular Formula: C4H11NO3 Molecular Weight (g/mol): 121.136 InChI Key: LENZDBCJOHFCAS-UHFFFAOYSA-N Synonym: Tris(hydroxymethyl)aminomethane PubChem CID: 6503 ChEBI: CHEBI:9754 IUPAC Name: 2-amino-2-(hydroxymethyl)propane-1,3-diol SMILES: C(C(CO)(CO)N)O

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Specifications

PubChem CID	6503
CAS	77-86-1
Molecular Weight (g/mol)	121.136
ChEBI	CHEBI:9754
SMILES	C(C(CO)(CO)N)O
Synonym	Tris(hydroxymethyl)aminomethane
IUPAC Name	2-amino-2-(hydroxymethyl)propane-1,3-diol
InChI Key	LENZDBCJOHFCAS-UHFFFAOYSA-N
Molecular Formula	C4H11NO3

442

HEPPS, MP Biomedicals™

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443

PIPES, 0.2M buffer soln., pH 7.0, low endotoxin, Thermo Scientific™

CAS: 5625-37-6 Molecular Formula: C8H18N2O6S2 Molecular Weight (g/mol): 302.36 MDL Number: MFCD00006159 InChI Key: IHPYMWDTONKSCO-UHFFFAOYSA-N PubChem CID: 79723 ChEBI: CHEBI:44933 IUPAC Name: 2-[4-(2-sulfoethyl)piperazin-1-yl]ethanesulfonic acid SMILES: C1CN(CCN1CCS(=O)(=O)O)CCS(=O)(=O)O

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Specifications

PubChem CID	79723
CAS	5625-37-6
Molecular Weight (g/mol)	302.36
ChEBI	CHEBI:44933
MDL Number	MFCD00006159
SMILES	C1CN(CCN1CCS(=O)(=O)O)CCS(=O)(=O)O
IUPAC Name	2-[4-(2-sulfoethyl)piperazin-1-yl]ethanesulfonic acid
InChI Key	IHPYMWDTONKSCO-UHFFFAOYSA-N
Molecular Formula	C8H18N2O6S2

444

Thermo Scientific Chemicals AMPSO, 98+%

CAS: 68399-79-1 Molecular Formula: C7H17NO5S Molecular Weight (g/mol): 227.28 MDL Number: MFCD00041777 InChI Key: ACERFIHBIWMFOR-UHFFFAOYNA-N Synonym: N-(1,1-Dimethyl-2-hydroxyethyl)-3-amino-2-hydroxypropanesulfonic acid PubChem CID: 100211 IUPAC Name: 2-hydroxy-3-[(1-hydroxy-2-methylpropan-2-yl)amino]propane-1-sulfonic acid SMILES: CC(C)(CO)NCC(O)CS(O)(=O)=O

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Specifications

PubChem CID	100211
CAS	68399-79-1
Molecular Weight (g/mol)	227.28
MDL Number	MFCD00041777
SMILES	CC(C)(CO)NCC(O)CS(O)(=O)=O
Synonym	N-(1,1-Dimethyl-2-hydroxyethyl)-3-amino-2-hydroxypropanesulfonic acid
IUPAC Name	2-hydroxy-3-[(1-hydroxy-2-methylpropan-2-yl)amino]propane-1-sulfonic acid
InChI Key	ACERFIHBIWMFOR-UHFFFAOYNA-N
Molecular Formula	C7H17NO5S

445

MES lysis buffer with Triton™ X-100, Thermo Scientific™

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Specifications

Health Hazard 3	P264b-P280i-P305+P351+P338
Color	Colorless
Physical Form	Liquid
Health Hazard 1	H319
Chemical Name or Material	MES lysis buffer with Triton™ X-100
TSCA	No
Recommended Storage	Keep cold

446

Tricine-buffered saline (5X), pH 7.0, Thermo Scientific™

CAS: 4-1-5704 Molecular Formula: C6H13NO5 Molecular Weight (g/mol): 179.17 MDL Number: MFCD00004277 InChI Key: SEQKRHFRPICQDD-UHFFFAOYSA-N PubChem CID: 79784 ChEBI: CHEBI:39063 IUPAC Name: 2-[[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino]acetic acid SMILES: C(C(=O)O)NC(CO)(CO)CO

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Specifications

PubChem CID	79784
CAS	4-1-5704
Molecular Weight (g/mol)	179.17
ChEBI	CHEBI:39063
MDL Number	MFCD00004277
SMILES	C(C(=O)O)NC(CO)(CO)CO
IUPAC Name	2-[[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino]acetic acid
InChI Key	SEQKRHFRPICQDD-UHFFFAOYSA-N
Molecular Formula	C6H13NO5

447

MOPSO Sodium Salt, MP Biomedicals™

CAS: 79803-73-9 Molecular Formula: C7H14NNaO5S Molecular Weight (g/mol): 247.24 InChI Key: WSFQLUVWDKCYSW-UHFFFAOYNA-M IUPAC Name: sodium 2-hydroxy-3-(morpholin-4-yl)propane-1-sulfonate SMILES: [Na+].OC(CN1CCOCC1)CS([O-])(=O)=O

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Specifications

CAS	79803-73-9
Molecular Weight (g/mol)	247.24
SMILES	[Na+].OC(CN1CCOCC1)CS([O-])(=O)=O
IUPAC Name	sodium 2-hydroxy-3-(morpholin-4-yl)propane-1-sulfonate
InChI Key	WSFQLUVWDKCYSW-UHFFFAOYNA-M
Molecular Formula	C7H14NNaO5S

448

HEPES, ≥99% (Dry Basis), Ultrapure

CAS: 7365-45-9 Molecular Formula: C8H18N2O4S Molecular Weight (g/mol): 238.30 MDL Number: MFCD00006158 InChI Key: JKMHFZQWWAIEOD-UHFFFAOYSA-N Synonym: N-[2-Hydroxyethyl]piperazine-N'-[2-Ethanesulfonic acid] PubChem CID: 23831 ChEBI: CHEBI:42334 IUPAC Name: 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid SMILES: OCCN1CCN(CCS(O)(=O)=O)CC1

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Specifications

PubChem CID	23831
CAS	7365-45-9
Molecular Weight (g/mol)	238.30
ChEBI	CHEBI:42334
MDL Number	MFCD00006158
SMILES	OCCN1CCN(CCS(O)(=O)=O)CC1
Synonym	N-[2-Hydroxyethyl]piperazine-N'-[2-Ethanesulfonic acid]
IUPAC Name	2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid
InChI Key	JKMHFZQWWAIEOD-UHFFFAOYSA-N
Molecular Formula	C8H18N2O4S

449

Tricine-SDS Sample Buffer (2X), non-reducing, Thermo Scientific™

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Specifications

Name Note	non-reducing
Health Hazard 3	GHS P Statement P280-P264-P305+P351+P338-P337+P313 Wear protective gloves/protective clothing/eye protection/face protection. Wash thoroughly after handling. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
Health Hazard 2	GHS H Statement H319 Causes serious eye irritation.
Color	Blue
Physical Form	Liquid
Health Hazard 1	H335
Chemical Name or Material	Tricine-SDS Sample Buffer
TSCA	Yes
Recommended Storage	Ambient temperatures
Concentration	2X

450

Thermo Scientific Chemicals Hanks' Balanced Salt Solution (10X), with calcium, with magnesium, with phenol red

Pricing & Availability
Specifications

Color	Red
Physical Form	Liquid
Recommended Storage	Ambient temperatures

Life Science Buffers

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